cherubims. The cherubim are evidently the highest in all the angelic hierarchy. Wherever they are encountered in Scripture, whether symbolically (e.g., Exodus 25:22) or actually (e.g., Ezekiel 10:19), they are seen to be guarding, as it were, the way into the presence of God (e.g., Genesis 3:24). Satan, or Lucifer, was originally the “anointed cherub” (Ezekiel 28:14), but forfeited this position when pride led him to sin against God (Ezekiel 28:16, 17).

great in Zion. In the New Jerusalem, following the last great judgment, “the throne of God and of the Lamb” (Revelation 22:3) will be at the center, “high above all the people.” From this high throne will flow down the “pure river of water of life” to water the earth (Revelation 22:1).

it is holy. The name of God is holy (Psalm 99:3), He is holy (Psalm 99:5), and on His holy hill, He is holy (Psalm 99:9). This thrice-holy God is, indeed, “high and lifted up” (Isaiah 6:1, 3). Note that the cherubim are present (Psalm 99:1), just as the seraphim (Isaiah 6:2).